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About the author, François DESBORDES |
|  François DESBORDESis veterinary doctor in Bretagne, a large French region of breeding, surrounded by the sea. This Breton inflamed by its profession, daily rubs elbows with bovine, porcine, poultry, horse, sheep breeders as well as aquaculture professionals. Veterinarian, its profession also leads him to look after dogs, cats and aviary birds.
Unweary researcher, he is since the beginning of his career inflamed by animal comfort and feed and declares his belonging to this current of Ecopathologist Veterinarians that was born in 1977 at Ploufragan in Bretagne.
His meeting with Bionov’s actors leads its researches to the superoxide dismutase SOD, melon enzyme.
In 2005, in relation with Bionov’s team, he creates PROMUTASE 200™, a raw material rich in melon SOD, and the websites :
www.promutase.com dedicated to animal feed and nutrition applications, and www.dismutase.fr , a knowledge portal about beneficial effects of the superoxide dismutase SOD.
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| super oxyde dismutase, superoxyde dismutase, dismmutase, dismutas, dissemutase, oxydant, antioxydant, enzime, oxydatif, radicall, mellon, S.O.D. | |
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| The dismutase.fr website and its content are copyright François Desbordes. Any reproduction, full or partial, of elements of this website without the express authorisation of the author is strictly prohibited. ©2007 | |
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Understanding the superoxide dismutases (SOD) |  |  These enzymes are present everywhere life is. So they are present in all animals with high levels, particularly in the red cells.
It is the same in humans where their real biological function was discovered in 1969 by Joe Mc Cord and Irwin Fridovich: the superoxide dismutases SOD allow us to fight against toxic waste of oxygen.
The superoxide dismutases SOD are also found in plants in more or less high quantities. But the more they are, there more resistant the plant is, the best the plant ages and the longer it is preserved!
These are properties that didn’t escape to the scientists.
The enthusiasm caused by this discovery comes from the high hopes evoked by the copper and zinc superoxide dismutases SOD, the most abundant in blood and cells.
Where do we find this SOD in quantities sufficient for feeding, nutrition, cosmetics, pharmacy?
Which source of SOD should we retain to allow durable development of its beneficial effects?
Animal extracts are dropped in almost all countries, in face of the dangers revealed by their use. Chimical synthesis of the superoxide dismutases SOD causes difficulties to the pharmaceutical research’s chemists. Sampling natural plants rapidly leads to an impasse by depletion of natural reserves.
 Rapid development of the melon SOD BIONOV is thus not a surprise since Bionov concentrates a melon juice particularly rich in SOD and makes it available to feeding, nutrition, cosmetics and pharmacy professionals.
Therefore, the superoxide dismutase SOD is an unfailing SOD source available in the whole world.
copyright dismutase.fr ©2006
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Vocabulary | | • Superoxide dismutase
We breathe oxigen to live, which is used by our cells to produce energy. But energy production goes with a low emission of toxic product, as a fire generates smoke. The toxic product is the superoxide anion. It is formed by the addition of one electron, negative electric charge, on molecular oxygen.
The Superoxide dismutase is a natural enzyme of the organism, able to neutralise superoxide anion very quickly.
• Free radicals
These chimical species, produced in our organism, have an odd number of electrons on the external orbital, as the superoxide anion. It gives them the property to react with other molecules by giving them the electron. That is what happens when iron rusts: it gives to air oxygen electrons.
That is why living organisms’ cells rust little by little with ageing, but also strongly in acute diseases or gradually in chronic diseases. Oxygen free radicals are called oxidants for that reason.
• Oxidative stress
Life is like a permanent burning fire. It produces more or less heat for our happiness and let a bit smoke escape, canalized by a good draught of the systems we use. When fire is no more under control, it can either burn everything or suffocate by excessive smoke production. Oxygen free radicals production, the oxidants of the organism, is canalized by the antioxidants’ action. A balance establishes just as in a heartily burning fireplace.
When this balance is disrupted, it is called oxidative stress.
• Enzyme
Numerous chemical reactions are quickened by miscellaneous substances. They are called catalysts. The proteins naturally produced in the living organism and having this property are biological catalysts, called enzymes.
Thus, superoxide anion is naturally knocked down slowly and partially, what gives it time to react with other molecules, causing considerable damage. In the presence of the superoxide dismutase enzyme, superoxide anion is eliminated 10 000 times faster!
• Antioxidant
These molecules are able to neutralize free radicals and to regulate their production. In the best of all possibilities, a balance sets up between oxidants and antioxidants.
The SOD, superoxide dismutase, is a major antioxidant enzyme, the anti-rust enzyme of the organism’s cells.
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